Open AccessCarboplatin and oxaliplatin decomposition in chloride medium, monitored by XAS
Author(s) -
Curis Emmanuel,
Provost Karine,
Bouvet Diane,
Nicolis Ioannis,
CrausteManciet Sylvie,
Brossard Denis,
Bénazeth Simone
Publication year - 2001
Publication title -
journal of synchrotron radiation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.172
H-Index - 99
ISSN - 1600-5775
DOI - 10.1107/s0909049500017775
Subject(s) - oxaliplatin , carboplatin , chemistry , aqueous solution , chloride , x ray absorption spectroscopy , decomposition , platinum , ion , inorganic chemistry , nuclear chemistry , cisplatin , organic chemistry , chemotherapy , surgery , medicine , absorption spectroscopy , cancer , physics , colorectal cancer , quantum mechanics , catalysis
The stability of carboplatin and oxaliplatin aqueous solutions has been studied under different chloride ions concentration and pH conditions. For both compounds, we demonstrate the chloration of the platinum first coordination shell.