The structure of chloramphenicol | Zendy

Ravindra Acharya K. | Zendy; Sake Gowda D. S. | Zendy; Post M. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

The structure of chloramphenicol

Author(s) -

Ravindra Acharya K.,

Sake Gowda D. S.,

Post M.

Publication year - 1979

Publication title -

acta crystallographica section b

Language(s) - English

Resource type - Journals

eISSN - 1600-5740

pISSN - 0567-7408

DOI - 10.1107/s0567740879006452

Subject(s) - orthorhombic crystal system , chloramphenicol , moiety , ring (chemistry) , alicyclic compound , crystallography , chemistry , side chain , stereochemistry , crystal structure , antibiotics , polymer chemistry , organic chemistry , biochemistry , polymer

The structure of chloramphenicol, C11H12Cl2N2O5, an important broad-spectrum antibiotic, was solved by direct methods and refined by Fourier and least-squares to a R of 0.069. The crystals are orthorhombic, space group C2221, with a 7.335(3), b 17.552(8), and c 22.159(6) Å; d.(calcd.) = 1.50 and d.(obsd.) = 1.49 for Z = 8. The side chain exists in the 'alicyclic' form, stabilized by H bonding between the hydroxyl groups. The dichloroacetamido moiety is folded back over the Ph ring

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research