Premium
Making the most of commercial sparse‐matrix protein crystallization screening kits
Author(s) -
Albert Armando,
MartínezRipoll Martín
Publication year - 1999
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s0021889898018366
Subject(s) - crystallization , solubility , matrix (chemical analysis) , protein crystallization , macromolecule , complex matrix , sample (material) , computer science , chemistry , materials science , chromatography , organic chemistry , biochemistry
A rational strategy to discern the solubility properties of a macromolecular sample is presented. The method uses the most popular crystallization screening kits. A small computer program has been developed to facilitate the analysis. Charts are included that show the dependence of the solubility on pH and precipitant concentrations.