Premium
A flexible approach to automated protein crystallization
Author(s) -
Oldfield T. J.,
Ceska T. A.,
Brady R. L.
Publication year - 1991
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s0021889891001632
Subject(s) - crystallization , microcomputer , polyethylene glycol , computer science , reproducibility , software , pipette , root mean square , protein crystallization , materials science , biological system , process engineering , chemical engineering , chromatography , chemistry , physics , operating system , engineering , telecommunications , chip , quantum mechanics , biology
An automated system for protein crystallization trials is described. Similar to commercial systems in operation, this system is readily assembled at a far lower cost. The software runs on either a microcomputer or a VAX and is both versatile and readily modified for special requirements. The system is capable of pipetting polyethylene glycol solutions accurately. Root‐mean‐square deviations in the accuracy of pipetted well solutions were similar to results obtained manually. Factors influencing reproducibility are discussed.