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Graphene as a protein crystal mounting material to reduce background scatter
Author(s) -
Wierman Jennifer L.,
Alden Jonathan S.,
Kim Chae Un,
McEuen Paul L.,
Gruner Sol M.
Publication year - 2013
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s002188981301786x
Subject(s) - graphene , protein crystallization , diffraction , crystal (programming language) , materials science , x ray crystallography , crystallography , optics , nanotechnology , physics , chemistry , computer science , crystallization , thermodynamics , programming language
The overall signal‐to‐noise ratio per unit dose for X‐ray diffraction data from protein crystals can be improved by reducing the mass and density of all material surrounding the crystals. This article demonstrates a path towards the practical ultimate in background reduction by use of atomically thin graphene sheets as a crystal mounting platform for protein crystals. The results show the potential for graphene in protein crystallography and other cases where X‐ray scatter from the mounting material must be reduced and specimen dehydration prevented, such as in coherent X‐ray diffraction imaging of microscopic objects.