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Permeability of water through a raft model membrane clarified by time‐resolved SANS and SAXS
Author(s) -
Hirai Mitsuhiro,
Onai Teruaki,
Koizumi Masaharu,
Hirai Harutaka,
Kasahara Kohji,
Suzuki Naoko,
Yuyama Kohei,
Inoue Katsuaki
Publication year - 2007
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s0021889806045729
Subject(s) - lamellar structure , small angle x ray scattering , vesicle , permeability (electromagnetism) , micelle , chemistry , raft , membrane , neutron scattering , phospholipid , small angle neutron scattering , chemical engineering , biophysics , crystallography , chromatography , scattering , copolymer , organic chemistry , aqueous solution , biochemistry , optics , physics , engineering , polymer , biology
We have characterized the structures of ganglioside (G D3 ) micelle and G D3 /cholesterol mixtures, and have determined the permeability of water across a membrane of G D3 /cholesterol/phospholipid uni‐lamellar vesicle. We have found that monovalent Na + and K + cations affect the permeability of water differently. We have found also that the permeability of water is greatly enhanced by the K + ion, suggesting the function of the G D3 /cholesterol rich clusters on neuronal excitations by K + . The complimentary use of small‐angle X‐ray and neutron scattering techniques is useful to determine the permeability of water across a vesicle membrane.