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Scattering from laterally heterogeneous vesicles. I. Model‐independent analysis
Author(s) -
Anghel Vinicius N. P.,
Pencer Jeremy,
Kučerka Norbert,
Katsaras John
Publication year - 2006
Publication title -
journal of applied crystallography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.429
H-Index - 162
ISSN - 1600-5767
DOI - 10.1107/s0021889806035163
Subject(s) - vesicle , scattering , invariant (physics) , membrane , small angle x ray scattering , chemistry , physics , molecular physics , optics , mathematical physics , biochemistry
This is the first of a series of papers considering the scattering from laterally heterogeneous vesicles. Here, it is shown that contrast variation studies on unilamellar vesicles can be analyzed in a model‐independent manner to detect lateral segregation in model membranes. In particular, it is demonstrated that the Porod invariant, Q = , is related to the scattering length density contrast between compositionally distinct regions in a heterogeneous membrane. The formation of domains and the concomitant identification of phase boundaries as a function of either membrane composition or temperature can therefore be detected in the changes taking place in Q .