The First Rule of Plant Transposable Element Silencing: Location, Location, Location | Zendy

Meredith J. Sigman | Zendy; R. Keith Slotkin | Zendy

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The First Rule of Plant Transposable Element Silencing: Location, Location, Location

Author(s) -

Meredith J. Sigman,

R. Keith Slotkin

Publication year - 2016

Publication title -

the plant cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.324

H-Index - 341

eISSN - 1532-298X

pISSN - 1040-4651

DOI - 10.1105/tpc.15.00869

Subject(s) - biology , transposable element , chromatin , genetics , gene silencing , centromere , epigenetics , gene , genome , chromosome , transposition (logic) , computational biology , linguistics , philosophy

Transposable elements (TEs) are mobile units of DNA that comprise large portions of plant genomes. Besides creating mutations via transposition and contributing to genome size, TEs play key roles in chromosome architecture and gene regulation. TE activity is repressed by overlapping mechanisms of chromatin condensation, epigenetic transcriptional silencing, and targeting by small interfering RNAs. The specific regulation of different TEs, as well as their different roles in chromosome architecture and gene regulation, is specified by where on the chromosome the TE is located: near a gene, within a gene, in a pericentromere/TE island, or at the centromere core. In this Review, we investigate the silencing mechanisms responsible for inhibiting TE activity for each of these chromosomal contexts, emphasizing that chromosomal location is the first rule dictating the specific regulation of each TE.

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