A Proposal Regarding Best Practices for Validating the Identity of Genetic Stocks and the Effects of Genetic Variants | Zendy

Joy Bergelson | Zendy; Edward S. Buckler | Zendy; Joseph R. Ecker | Zendy; Magnus Nordborg | Zendy; Detlef Weigel | Zendy

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A Proposal Regarding Best Practices for Validating the Identity of Genetic Stocks and the Effects of Genetic Variants

Author(s) -

Joy Bergelson,

Edward S. Buckler,

Joseph R. Ecker,

Magnus Nordborg,

Detlef Weigel

Publication year - 2016

Publication title -

the plant cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.324

H-Index - 341

eISSN - 1532-298X

pISSN - 1040-4651

DOI - 10.1105/tpc.15.00502

Subject(s) - biology , identity (music) , genetics , field (mathematics) , microbiology and biotechnology , computational biology , evolutionary biology , physics , acoustics , mathematics , pure mathematics

Colleagues from the medical field have estimated that up to one-third of cell lines are contaminated with other cell lines or are misidentified; in addition, repeated passaging substantially changes cell line properties (reviewed in [Hughes et al., 2007][1]). The medical community has therefore

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