Advancing Genetic Theory and Application by Metabolic Quantitative Trait Loci Analysis | Zendy

Daniel J. Kliebenstein | Zendy

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Advancing Genetic Theory and Application by Metabolic Quantitative Trait Loci Analysis

Author(s) -

Daniel J. Kliebenstein

Publication year - 2009

Publication title -

the plant cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.324

H-Index - 341

eISSN - 1532-298X

pISSN - 1040-4651

DOI - 10.1105/tpc.109.067611

Subject(s) - quantitative trait locus , epistasis , biology , genetic architecture , quantitative genetics , family based qtl mapping , trait , evolutionary biology , genetic analysis , genetics , genetic variation , computational biology , gene mapping , gene , computer science , programming language , chromosome

This review describes recent advances in the analysis of metabolism using quantitative genetics. It focuses on how recent metabolic quantitative trait loci (QTL) studies enhance our understanding of the genetic architecture underlying naturally variable phenotypes and the impact of this fundamental research on agriculture, specifically crop breeding. In particular, the role of whole-genome duplications in generating quantitative genetic variation within a species is highlighted and the potential uses of this phenomenon presented. Additionally, the review describes how new observations from metabolic QTL mapping analyses are helping to shape and expand the concepts of genetic epistasis.

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