Open AccessThe Gene Balance Hypothesis: From Classical Genetics to Modern Genomics
Author(s) -
James A. Birchler,
Reiner A. Veitia
Publication year - 2007
Publication title -
the plant cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.324
H-Index - 341
eISSN - 1532-298X
pISSN - 1040-4651
DOI - 10.1105/tpc.106.049338
Subject(s) - biology , ploidy , genetics , aneuploidy , phenotype , gene , karyotype , genome , chromosome , gene dosage , balance (ability) , gene expression , neuroscience
The concept of genetic balance traces back to the early days of genetics. Additions or subtractions of single chromosomes to the karyotype (aneuploidy) produced greater impacts on the phenotype than whole-genome changes (ploidy). Studies on changes in gene expression in aneuploid and ploidy series
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