Molybdenum Cofactor Mutants, Specifically Impaired in Xanthine Dehydrogenase Activity and Abscisic Acid Biosynthesis, Simultaneously Overexpress Nitrate Reductase | Zendy

M.T. Leydecker | Zendy; Thérèse Moureaux | Zendy; Yvan Kraepiel | Zendy; Kirk Schnorr | Zendy; Michel Caboche | Zendy

Open Access

Molybdenum Cofactor Mutants, Specifically Impaired in Xanthine Dehydrogenase Activity and Abscisic Acid Biosynthesis, Simultaneously Overexpress Nitrate Reductase

Author(s) -

M.T. Leydecker,

Thérèse Moureaux,

Yvan Kraepiel,

Kirk Schnorr,

Michel Caboche

Publication year - 1995

Publication title -

plant physiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.554

H-Index - 312

eISSN - 1532-2548

pISSN - 0032-0889

DOI - 10.1104/pp.107.4.1427

Subject(s) - aldehyde oxidase , molybdenum cofactor , xanthine dehydrogenase , nitrate reductase , abscisic acid , biochemistry , cofactor , biosynthesis , mutant , xanthine oxidase , chemistry , dehydrogenase , enzyme , reductase , oxidase test , gene

The molybdenum cofactor is shared by nitrate reductase (NR), xanthine dehydrogenase (XDH), and abscisic acid (ABA) aldehyde oxidase in higher plants (M. Walker-Simmons, D.A. Kudrna, R.L. Warner [1989] Plant Physiol 90:728-733). In agreement with this, cnx mutants are simultaneously deficient for these three enzyme activities and have physiological characteristics of ABA-deficient plants. In this report we show that aba1 mutants, initially characterized as ABA-deficient mutants, are impaired in both ABA aldehyde oxidase and XDH activity but overexpress NR. These characteristics suggest that aba1 is in fact involved in the last step of molybdenum cofactor biosynthesis specific to XDH and ABA aldehyde oxidase; aba1 probably has the same function as hxB in Aspergillus. The significance of NR overexpression in aba1 mutants is discussed.

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