Design Automation in Synthetic Biology | Zendy

Evan Appleton | Zendy; Curtis Madsen | Zendy; Nicholas Roehner | Zendy; Douglas Densmore | Zendy

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Design Automation in Synthetic Biology

Author(s) -

Evan Appleton,

Curtis Madsen,

Nicholas Roehner,

Douglas Densmore

Publication year - 2017

Publication title -

cold spring harbor perspectives in biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.011

H-Index - 173

ISSN - 1943-0264

DOI - 10.1101/cshperspect.a023978

Subject(s) - workflow , automation , synthetic biology , software , software engineering , computer science , biology , systems engineering , data science , computational biology , engineering , programming language , database , mechanical engineering

Design automation refers to a category of software tools for designing systems that work together in a workflow for designing, building, testing, and analyzing systems with a target behavior. In synthetic biology, these tools are called bio-design automation (BDA) tools. In this review, we discuss the BDA tools areas-specify, design, build, test, and learn-and introduce the existing software tools designed to solve problems in these areas. We then detail the functionality of some of these tools and show how they can be used together to create the desired behavior of two types of modern synthetic genetic regulatory networks.

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