Not Just Fat: The Structure and Function of the Lipid Droplet | Zendy

Toyoshi Fujimoto | Zendy; Robert G. Parton | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Not Just Fat: The Structure and Function of the Lipid Droplet

Author(s) -

Toyoshi Fujimoto,

Robert G. Parton

Publication year - 2011

Publication title -

cold spring harbor perspectives in biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.011

H-Index - 173

ISSN - 1943-0264

DOI - 10.1101/cshperspect.a004838

Subject(s) - organelle , biology , lipid droplet , phospholipid , context (archaeology) , lipid metabolism , function (biology) , lipid bilayer , biophysics , biochemistry , microbiology and biotechnology , membrane , paleontology

Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and a surface phospholipid monolayer. Recent studies have revealed many new proteins, functions, and phenomena associated with LDs. In addition, a number of diseases related to LDs are beginning to be understood at the molecular level. It is now clear that LDs are not an inert store of excess lipids but are dynamically engaged in various cellular functions, some of which are not directly related to lipid metabolism. Compared to conventional membrane organelles, there are still many uncertainties concerning the molecular architecture of LDs and how each function is placed in a structural context. Recent findings and remaining questions are discussed.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research