Understanding the Structure and Function of the Immunological Synapse
Author(s) -
Michael L. Dustin,
Arup K. Chakraborty,
Andréy S. Shaw
Publication year - 2010
Publication title -
cold spring harbor perspectives in biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.011
H-Index - 173
ISSN - 1943-0264
DOI - 10.1101/cshperspect.a002311
Subject(s) - immunological synapse , biology , synapse , neuroscience , function (biology) , t cell , microbiology and biotechnology , immune system , immunology , t cell receptor
The immunological synapse has been an area of very active scientific interest over the last decade. Surprisingly, much about the synapse remains unknown or is controversial. Here we review some of these current issues in the field: how the synapse is defined, its potential role in T-cell function, and our current understanding about how the synapse is formed
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