Open AccessWidely Conserved Signaling Pathways in the Establishment of Cell Polarity
Author(s) -
Luke McCaffrey,
Ian G. Macara
Publication year - 2009
Publication title -
cold spring harbor perspectives in biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.011
H-Index - 173
ISSN - 1943-0264
DOI - 10.1101/cshperspect.a001370
Subject(s) - biology , cell polarity , polarity (international relations) , signal transduction , microbiology and biotechnology , gtpase , cell , signaling proteins , cell signaling , kinase , protein serine threonine kinases , protein kinase a , genetics
How are the asymmetric distributions of proteins, lipids, and RNAs established and maintained in various cell types? Studies from diverse organisms show that Par proteins, GTPases, kinases, and phosphoinositides participate in conserved signaling pathways to establish and maintain cell polarity.
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