Open AccessLactic acid bacterial exopolysaccharides strongly bind histamine and can potentially be used to remove histamine contamination in food
Author(s) -
Hideki Kinoshita,
Moe Hariu,
Yuki Nakashima,
Kohei Watanabe,
Shin Yasuda,
Keiji Igoshi
Publication year - 2021
Publication title -
microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.352
H-Index - 35
eISSN - 1465-2080
pISSN - 1350-0872
DOI - 10.1099/mic.0.000936
Subject(s) - histamine , lactobacillus paracasei , chemistry , food science , lactobacillus plantarum , food poisoning , probiotic , leuconostoc mesenteroides , lactic acid , lactobacillus , langmuir , microbiology and biotechnology , bacteria , adsorption , fermentation , biology , pharmacology , organic chemistry , genetics
The symptoms of foodborne histamine poisoning are similar to those of IgE-mediated food allergies. In this study, we investigated the histamine-binding capacity of lactic acid bacteria (LAB) strains as potential preventive agents against histamine poisoning. Histamine biosorption capacity was determined for 16 LAB strains. Leuconostoc mesenteroides TOKAI 51 m, Lactobacillus paracasei TOKAI 65 m, Lactobacillus plantarum TOKAI 111 m and Pediococcus pentosaceus TOKAI 759 m showed especially high biosorption rates and reached saturation within 30 min. Adsorption isotherms showed better conformance to the Freundlich model than to the Langmuir model. Analyses after heat, periodic acid and guanidine hydrochloride treatments suggested that histamine was bound to the bacterial cell surface. HPLC analysis revealed that exopolysaccharides produced by Lact. paracasei TOKAI 65 m strongly bound to histamine. In the detachment test with 1 mol l −1 HCl solution, the dissociation rate of histamine for Lact. paracasei TOKAI 65 m was <10 %. This strain is presumably a suitable candidate for use against histamine poisoning.