Open AccessWhole genome sequence analysis of Shigella from Malawi identifies fluoroquinolone resistance
Author(s) -
George E. Stenhouse,
Khuzwayo C. Jere,
Chikondi Peno,
Rebecca J. Bengtsson,
End Chinyama,
Jonathan Mandolo,
Amy K. Cain,
Miren IturrizaGómara,
Naor Bar-Zeev,
Nigel A. Cunliffe,
Jennifer Cornick,
Kate S. Baker
Publication year - 2021
Publication title -
microbial genomics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.476
H-Index - 28
ISSN - 2057-5858
DOI - 10.1099/mgen.0.000532
Subject(s) - shigella , whole genome sequencing , biology , antibiotic resistance , genome , microbiology and biotechnology , genetics , salmonella , bacteria , gene , antibiotics
Increasing antimicrobial resistance and limited alternative treatments have led to fluoroquinolone-resistant Shigella strain inclusion on the WHO global priority pathogens list. In this study we characterized multiple Shigella isolates from Malawi with whole genome sequence analysis, identifying the acquirable fluoroquinolone resistance determinant qnrS1 .