Open AccessOral microbial dysbiosis in patients with Kostmann syndrome
Author(s) -
Nursen Topçuoğlu,
Arzu Pınar Erdem,
İlker Karacan,
Güven Külekçi
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000964
Subject(s) - biology , dysbiosis , actinomyces , oral microbiome , microbiome , prevotella , proteobacteria , firmicutes , fusobacteria , immunology , microbiology and biotechnology , genetics , 16s ribosomal rna , gene , bacteria
The oral microbiome is maintained by host- and microbe-derived factors. A shift in microbial composition, as a result of diseases related to the immune system, is the most important step in the development of oral and dental diseases. The aim of this study was to investigate the oral microbial composition of patients with Kostmann syndrome, who have severe neutropenia, compared with healthy children.