Open AccessIdentification of Pythium insidiosum complex by matrix-assisted laser desorption ionization-time of flight mass spectrometry
Author(s) -
Rinosh Mani,
Raquel Vilela,
Niesa Kettler,
Martin I. Chilvers,
Leonel Mendoza
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000941
Subject(s) - biology , microbiology and biotechnology , pathogen , pythium , hypha , matrix assisted laser desorption/ionization , botany , chemistry , organic chemistry , adsorption , desorption
Pythiosis is an infection of humans and other animals caused by the fungal-like pathogen Pythium insidiosum. This pathogen causes life-threatening infection in the infected hosts. Culture, histopathology, serology and molecular tools are used to diagnose its infections. Successful management of pythiosis is directly linked to an early diagnosis. Thus, a rapid identification of putative cultures developing submerged sparsely septate hyphae is of extreme importance. However, few laboratories are familiar with the culture identification of this unique pathogen and its differential diagnosis with similar filamentous fungi.