Heat-treated Lactobacillus plantarum increases the immune responses through activation of natural killer cells and macrophages on in vivo and in vitro models | Zendy

PhilDong Moon | Zendy; Jin Soo Lee | Zendy; HeeYun Kim | Zendy; NaRa Han | Zendy; Inyeong Kang | Zendy; HyungMin Kim | Zendy; HyunJa Jeong | Zendy

Open Access

Heat-treated Lactobacillus plantarum increases the immune responses through activation of natural killer cells and macrophages on in vivo and in vitro models

Author(s) -

PhilDong Moon,

Jin Soo Lee,

HeeYun Kim,

NaRa Han,

Inyeong Kang,

HyungMin Kim,

HyunJa Jeong

Publication year - 2019

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000938

Subject(s) - immune system , interleukin 12 , tumor necrosis factor alpha , biology , in vivo , immunology , innate immune system , natural killer cell , microbiology and biotechnology , in vitro , cytotoxicity , cytotoxic t cell , biochemistry

Recently, Lactobacillus plantarum (nF1) has been reported to have immune-enhancing effects in an immunosuppressed-animal model. Natural killer (NK) cells and macrophages play important roles in the immune responses. However, immunomodulatory effects of heat-treated Lactobacillus plantarum-nF1 (hLp-nF1) on the activation of NK cells and macrophages have not been elucidated.

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