Open AccessEvaluation of a novel immunochromatographic lateral flow assay for rapid detection of OXA-48, NDM, KPC and VIM carbapenemases in multidrug-resistant Enterobacteriaceae
Author(s) -
Stephan Rösner,
Shilpa Kamalanabhaiah,
Uta Küsters,
Mathias Kolbert,
Niels Pfennigwerth,
Dietrich Mack
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000925
Subject(s) - clinical microbiology , multiplex , microbiology and biotechnology , turnaround time , enterobacteriaceae , multiple drug resistance , antibiotics , biology , medicine , computer science , bioinformatics , escherichia coli , biochemistry , operating system , gene
The global spread and increasing clinical impact of carbapenemase-producing bacteria are alarming. Rapid diagnostic techniques for carbapenemase detection are of the utmost importance to prevent delays in efficient antibiotic therapy and the control of spread in hospitals. Recently, multiplex immunochromatographic lateral flow tests (ICTs) for the fast detection of carbapenemase-producers have become commercially available. We evaluated a novel multiplex ICT for the rapid detection of OXA-48, KPC, NDM and VIM carbapenemases.