Open AccessSynergistic activity of polymyxin B combined with vancomycin against carbapenem-resistant and polymyxin-resistant Acinetobacter baumannii: first in vitro study
Author(s) -
Danielle Rosani Shinohara,
Thatiany Cevallos Menegucci,
Nayara Helisandra Fedrigo,
Letícia Busato Migliorini,
Floristher Elaine Carrara-Marroni,
Márcia Maria dos Anjos,
Celso Luíz Cardoso,
Sheila Alexandra Belini Nishiyama,
Maria Cristina Bronharo Tognim
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000920
Subject(s) - acinetobacter baumannii , polymyxin , microbiology and biotechnology , polymyxin b , vancomycin , carbapenem , acinetobacter , in vitro , antibiotics , biology , medicine , bacteria , pseudomonas aeruginosa , staphylococcus aureus , biochemistry , genetics
The effect of a combination of polymyxin B (PMB) and vancomycin (VAN) was assessed against six Acinetobacter baumannii clinical isolates belonging to six different clusters (three PMB-susceptible and three PMB-resistant).