Open AccessInvestigation of fluoroquinolone resistance mechanism in Mycoplasma hominis isolated from urogenital samples in a Chinese hospital
Author(s) -
Hongyan Zhang,
Liangjian Zheng,
Juan Zhao,
Shaochuan Ding,
Yun Xia
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000913
Subject(s) - mycoplasma hominis , topoisomerase iv , dna gyrase , biology , microbiology and biotechnology , broth microdilution , gatifloxacin , ofloxacin , quinolone , levofloxacin , gene , virology , ciprofloxacin , genetics , antibiotics , mycoplasma , minimum inhibitory concentration , escherichia coli
Mycoplasma hominis is considered among the causes of urogenital infections and shows increasing resistance to fluoroquinolones. However, data regarding the fluoroquinolone resistance mechanism of M. hominis in Southwest China are limited. This study aimed to investigate gene mutations of quinolone resistance-determining regions (QRDRs) of M. hominis isolated from clinical urogenital samples in a Chinese hospital.