Open AccessLimited efficacy of nontreponemal test combined with treponemal test in the initial syphilis screening algorithm
Author(s) -
C. Gambiez,
C. Garet,
Morgane Choquet,
Véronique Decroix,
E. Pluquet,
Raphaël Guihéneuf,
Sandrine Castelain
Publication year - 2019
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000886
Subject(s) - syphilis , medicine , immunoassay , treponema , algorithm , immunology , antibody , computer science , human immunodeficiency virus (hiv)
Various syphilis screening algorithms have been proposed and are now used by many clinical laboratories following the introduction of automated treponemal tests (TTs). In France, the diagnosis of syphilis is based on a TT combined with a nontreponemal test (NTT). The objective of this study was to evaluate the diagnostic impact of NTT on initial syphilis screening at the Amiens University Hospital between January 2013 and December 2016.