Characterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada | Zendy

Michael R. Mulvey | Zendy; Amrita Bharat | Zendy; David A. Boyd | Zendy; Rebecca Irwin | Zendy; John Wylie | Zendy

Open Access

Characterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada

Author(s) -

Michael R. Mulvey,

Amrita Bharat,

David A. Boyd,

Rebecca Irwin,

John Wylie

Publication year - 2018

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000854

Subject(s) - salmonella enterica , colistin , amikacin , microbiology and biotechnology , salmonella , plasmid , piperacillin/tazobactam , piperacillin , mcr 1 , biology , clone (java method) , serotype , tazobactam , virology , enterobacteriaceae , antibiotic resistance , antibiotics , escherichia coli , bacteria , gene , genetics , imipenem , pseudomonas aeruginosa

We have identified a Salmonella enterica serotype 4,[5],12:i:- containing a mcr-3.2 in a patient who travelled to Thailand 1 month prior to the identification of it in Canada. The isolate was multidrug resistant, but remained susceptible to the carbapenems, amikacin and piperacillin/tazobactam. The mcr-3.2 was carried on a 261 Kb variant of the IncHI2 pWJ1. This report provides further evidence of the emergence of a ST34 colistin-resistant clone.

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