Open AccessCharacterization of a colistin-resistant Salmonella enterica 4,[5],12:i:- harbouring mcr-3.2 on a variant IncHI-2 plasmid identified in Canada
Author(s) -
Michael R. Mulvey,
Amrita Bharat,
David A. Boyd,
Rebecca Irwin,
John Wylie
Publication year - 2018
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000854
Subject(s) - salmonella enterica , colistin , amikacin , microbiology and biotechnology , salmonella , plasmid , piperacillin/tazobactam , piperacillin , mcr 1 , biology , clone (java method) , serotype , tazobactam , virology , enterobacteriaceae , antibiotic resistance , antibiotics , escherichia coli , bacteria , gene , genetics , imipenem , pseudomonas aeruginosa
We have identified a Salmonella enterica serotype 4,[5],12:i:- containing a mcr-3.2 in a patient who travelled to Thailand 1 month prior to the identification of it in Canada. The isolate was multidrug resistant, but remained susceptible to the carbapenems, amikacin and piperacillin/tazobactam. The mcr-3.2 was carried on a 261 Kb variant of the IncHI2 pWJ1. This report provides further evidence of the emergence of a ST34 colistin-resistant clone.