Open AccessClioquinol is a promising preventive morphological switching compound in the treatment of Candida infections linked to the use of intrauterine devices
Author(s) -
Bruna Pippi,
Gabriella da Rosa Monte Machado,
Vanessa Zafaneli Bergamo,
Ricardo José Alves,
Saulo Fernandes de Andrade,
Alexandre Meneghello Fuentefría
Publication year - 2018
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000850
Subject(s) - clioquinol , biofilm , microbiology and biotechnology , chemistry , pharmacology , fluconazole , antifungal , medicine , biology , bacteria , genetics
Candida biofilm infections are frequently linked to the use of biomaterials and are of clinical significance because they are commonly resistant to antifungals. Clioquinol is an antiseptic drug and is effective against multidrug-resistant Candida. We investigated the effect of clioquinol and two other 8-hydroxyquinoline derivatives on Candida biofilm.