Open AccessIcelandic ovine Mycoplasma ovipneumoniae are variable bacteria that induce limited immune responses in vitro and in vivo
Author(s) -
Thorbjorg Einarsdottir,
Eggert Gunnarsson,
Sigríður Hjartardóttir
Publication year - 2018
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000818
Subject(s) - biology , vaccination , immune system , microbiology and biotechnology , antibody , mycoplasma , pathogen , bacteria , intracellular parasite , immunology , humoral immunity , virology , in vivo , mycoplasmataceae , mollicutes , genetics
Mycoplasma ovipneumoniae is a pathogen that causes atypical pneumoniae in sheep and goats. While infection of lambs can induce strong immune responses, typically measured as serum antibodies, experimental vaccines appear to induce lower antibody titres. The purpose of this study was to better understand the bacterium and its interaction with the host, in order to improve the vaccination strategy.