Open AccessGlobal survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases
Author(s) -
Mark G. Wise,
Elizabeth Horvath,
Katherine Young,
Daniel F. Sahm,
Krystyna M. Kazmierczak
Publication year - 2018
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000691
Subject(s) - ertapenem , klebsiella pneumoniae , porin , microbiology and biotechnology , biology , carbapenem , klebsiella , gene , bacterial outer membrane , escherichia coli , genetics , antibiotics
To understand the diversity of porin disruption in Klebsiella pneumoniae, the major outer membrane protein (OMP) porins, OmpK35 and OmpK36, were examined in a set of isolates that did not harbour traditional carbapenem-hydrolysing enzymes, but nevertheless tested non-susceptible to ertapenem.