Global survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases | Zendy

Mark G. Wise | Zendy; Elizabeth Horvath | Zendy; Katherine Young | Zendy; Daniel F. Sahm | Zendy; Krystyna M. Kazmierczak | Zendy

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Global survey of Klebsiella pneumoniae major porins from ertapenem non-susceptible isolates lacking carbapenemases

Author(s) -

Mark G. Wise,

Elizabeth Horvath,

Katherine Young,

Daniel F. Sahm,

Krystyna M. Kazmierczak

Publication year - 2018

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000691

Subject(s) - ertapenem , klebsiella pneumoniae , porin , microbiology and biotechnology , biology , carbapenem , klebsiella , gene , bacterial outer membrane , escherichia coli , genetics , antibiotics

To understand the diversity of porin disruption in Klebsiella pneumoniae, the major outer membrane protein (OMP) porins, OmpK35 and OmpK36, were examined in a set of isolates that did not harbour traditional carbapenem-hydrolysing enzymes, but nevertheless tested non-susceptible to ertapenem.

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