The double adjuvants LTB and CpG significantly enhanced the immuno-protective effects of recombinant GIT derived from Staphylococcus aureus and Streptococcus in mice | Zendy

Jinzhu Ma | Zendy; Liquan Yu | Zendy; Baifen Song | Zendy; Yongzhong Yu | Zendy; Shaoduo Zhang | Zendy; Yu-Hua Wei | Zendy; ZhiJun Wu | Zendy; Di Yao | Zendy; Wei Yu | Zendy; Zhanbo Zhu | Zendy; Yudong Cui | Zendy

Open Access

The double adjuvants LTB and CpG significantly enhanced the immuno-protective effects of recombinant GIT derived from Staphylococcus aureus and Streptococcus in mice

Author(s) -

Jinzhu Ma,

Liquan Yu,

Baifen Song,

Yongzhong Yu,

Shaoduo Zhang,

Yu-Hua Wei,

ZhiJun Wu,

Di Yao,

Wei Yu,

Zhanbo Zhu,

Yudong Cui

Publication year - 2018

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000666

Subject(s) - cpg oligodeoxynucleotide , adjuvant , immunogenicity , biology , microbiology and biotechnology , antigen , antibody , cpg site , enterotoxin , immune system , immunization , immunology , gene expression , gene , escherichia coli , dna methylation , biochemistry

In this study, we prepared GapC1-150-IsdB126-361-TRAP (GIT) proteins plus heat-labile enterotoxin B (LTB) as an intra-molecular adjuvant, together with CpG to further enhance its immunogenicity.

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