Open AccessSARS-CoV-2 Spike has broad tropism for mammalian ACE2 proteins yet exhibits a distinct pattern of receptor usage when compared to other β-coronavirus Spike proteins
Author(s) -
Carina Conceicao,
Nazia Thakur,
Stacey Human,
James T. Kelly,
Leanne Logan,
Dagmara Bialy,
Sushant Bhat,
Phoebe Stevenson-Leggett,
Adrian K. Zagrajek,
Philippa Hollinghurst,
Michal Varga,
Christina Tsirigoti,
Matthew Tully,
Chris Chiu,
Katy Moffat,
Adrian Paul Silesian,
John A. Hammond,
Helena J. Maier,
Erica Bickerton,
Holly Shelton,
Isabelle Dietrich,
Stephen C. Graham,
Dalan Bailey
Publication year - 2022
Publication title -
access microbiology
Language(s) - English
Resource type - Journals
ISSN - 2516-8290
DOI - 10.1099/acmi.ac2021.po0441
Subject(s) - tropism , coronavirus , biology , virology , tissue tropism , virus , viral entry , angiotensin converting enzyme 2 , covid-19 , receptor , betacoronavirus , spike protein , spike (software development) , genetics , viral replication , disease , medicine , infectious disease (medical specialty) , pathology , management , economics