Development of a protocol for detection of SARS-CoV-2 in sputum and endotracheal aspirates using Cepheid Xpert Xpress SARS-CoV-2 | Zendy

Michael Malczynski | Zendy; Saba Rezaeian | Zendy; Javier Rios | Zendy; Laura Dirnberger | Zendy; Wanda Polanco | Zendy; Teresa Zembower | Zendy; Chao Qi | Zendy

Open Access

Development of a protocol for detection of SARS-CoV-2 in sputum and endotracheal aspirates using Cepheid Xpert Xpress SARS-CoV-2

Author(s) -

Michael Malczynski,

Saba Rezaeian,

Javier Rios,

Laura Dirnberger,

Wanda Polanco,

Teresa Zembower,

Chao Qi

Publication year - 2020

Publication title -

access microbiology

Language(s) - English

Resource type - Journals

ISSN - 2516-8290

DOI - 10.1099/acmi.0.000176

Subject(s) - sputum , medicine , covid-19 , respiratory tract , coronavirus , virology , cepheid variable , respiratory system , tuberculosis , pathology , infectious disease (medical specialty) , disease , stars , physics , astronomy , outbreak

Sputum and endotracheal aspirates (ETs) are not among the vendor-approved specimens for the Cepheid Xpert SARS-CoV-2 assay. However, they are the common lower respiratory tract specimens submitted for laboratory diagnosis. Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in lower respiratory tract samples is required for the discharge of patients from coronavirus disease (COVID) units at some institutions. We developed a protocol used for testing unliquified viscous sputum or tracheal aspirate with the Cepheid Xpert SARS-CoV-2 assay.

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