
Isolation and identification of Streptococcus pneumoniae serotype 6B from a patient with bacterial meningitis infection in Jakarta, Indonesia
Author(s) -
Diana Shintawati Purwanto,
Tonny Loho,
Wisnu Tafroji,
Irawan Mangunatmadja,
Suzanna Immanuel,
Ina Susianti Timan,
Yusra Yusra,
Dodi Safari
Publication year - 2020
Publication title -
access microbiology
Language(s) - English
Resource type - Journals
ISSN - 2516-8290
DOI - 10.1099/acmi.0.000123
Subject(s) - streptococcus pneumoniae , meningitis , serotype , penicillin , microbiology and biotechnology , medicine , isolation (microbiology) , antibiotics , biology , pediatrics
CNS infection is a life-threatening condition in developing countries andStreptococcus pneumoniaehas been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identityS. pneumoniaestrains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017.S. pneumoniaeisolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, oneS. pneumoniaestrain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data provide insights into the epidemiology of invasive pneumococcal disease in Indonesia.