Open AccessThe case report of Mycobacterium arupense wound infection in diabetes mellitus patients; the first report and literature review
Author(s) -
Sepehr Navid,
Bahar Sadegh-Ehdaei,
Maryam Shabani,
Melika Hasani,
Arezoo Mirzaei,
Kiarash Ghazvini,
Masoud Youssefi,
Mohsen Karbalaei
Publication year - 2020
Publication title -
access microbiology
Language(s) - English
Resource type - Journals
ISSN - 2516-8290
DOI - 10.1099/acmi.0.000106
Subject(s) - rifabutin , ethambutol , clarithromycin , medicine , diabetes mellitus , mycobacterium , lesion , mycobacterium chelonae , dermatology , microbiology and biotechnology , tuberculosis , pathology , isoniazid , biology , helicobacter pylori , endocrinology
Mycobacterium arupenseis among the opportunist pathogens of atypical mycobacteria emergence (atypical mycobacteria) that is one of the isolated and reported environmental and clinical specimens. Numerous cases of osteo-articular infections of this bacterium are reported nowadays, while the pulmonary infection is rare. We identifiedMycobacterium arupensein non-healing wound infection of an elderly woman with history of diabetes mellitus. She has negative tests for HIV, HBV and HCV, but was positive for HTLV-1. The patient was referred according to mild-fever, non-healing, destructive, and swelled lesion on her left foot. The mycobacterial wounds infection was suspected due to her non-conclusive previous treatment. The pathology, acid-fast staining, conventional and 16S rRNA sequencing confirmed the micro-organism to beM. arupense . Finally, the patient recovered following two-week consumption of clarithromycin, ethambutol and rifabutin. The results of this study provide evidence on the potential pathogenicity, clinical outcomes and treatment of infections caused by this bacterium.