Open AccessEcology of Pseudomonas aeruginosa in patients with cystic fibrosis
Author(s) -
A. M. Horrevorts,
Jan Willem Borst,
R. J. T. Puyk,
Rogier de Ridder,
G. Dzoljic-Danilovic,
John E. Degener,
Karel Kerrebijn,
M. F. Michel
Publication year - 1990
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-31-2-119
Subject(s) - pseudomonas aeruginosa , serotype , sputum , cystic fibrosis , microbiology and biotechnology , typing , phage typing , biology , pseudomonadaceae , virology , medicine , bacteria , pathology , genetics , tuberculosis
The occurrence of various Pseudomonas aeruginosa strains in the sputum of 15 patients with cystic fibrosis (CF) was monitored over periods ranging from 2 to 60 months. Isolates of P. aeruginosa were typed by four different techniques, namely serotyping, active and passive pyocin typing, and phage typing. The maximum number of different serotypes found in the patients was three (one serotype in nine patients; two serotypes in five patients; three serotypes in one patient). Pyocin and phage typing showed no marked differences between strains of the same serotype in individual patients. Exacerbations of chronic respiratory infection were not associated with changes in the sputum flora, the composition of P. aeruginosa strains in which remains constant over long periods in patients with CF.