Open AccessUrethral infection of chimpanzees by Ureaplasma urealyticum
Author(s) -
David TaylorRobinson,
Robert H. Purcell,
Warren London,
D. L. Sly
Publication year - 1978
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-11-2-197
Subject(s) - ureaplasma urealyticum , urethritis , tetracycline , serotype , ureaplasma , microbiology and biotechnology , biology , strain (injury) , throat , virology , mycoplasmataceae , mollicutes , mycoplasma , medicine , antibiotics , anatomy
Two strains of Ureaplasma urealyticum serotype V that had produced urethritis in human volunteers were, after a number of subcultures in artificial media, introduced intra-urethrally into three chimpanzees. One strain given to two chimpanzees rapidly multiplied 1000-fold whereas there was less evidence that organisms of another strain multiplied in a third animal. Over a 14-day period the ureaplasmas persisted in all animals, did not spread to the throat and did not produce an inflammatory response. After this time they were eliminated by tetracycline therapy.