Open AccessPriming Increases the Amount of Interferon mRNA in Poly(rI).poly(rC)-treated L Cells
Author(s) -
Takashi Fujita,
Sakura Saito,
Seiya Kohno
Publication year - 1979
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/0022-1317-45-2-301
Subject(s) - interferon , biology , priming (agriculture) , messenger rna , microbiology and biotechnology , virology , biochemistry , gene , botany , germination
Priming by mouse interferon pre-treatment resulted in an accumulation of interferon mRNA in poly(rI).poly(rC)-treated L cells, starting early in the period of interferon synthesis. On electrophoresis, the priming activity of an interferon preparation co-migrated with the antiviral activity, which suggests identity of the functional principle(s) for these activities.