Open AccessGenetic Relationship between an Influenza A and a B Virus
Author(s) -
Christoph Scholtissek,
Wolfgang Rohde,
E. Harms
Publication year - 1977
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/0022-1317-37-2-243
Subject(s) - biology , virology , virus , homology (biology) , rna , h5n1 genetic structure , sequence homology , genetics , gene , base sequence , covid-19 , infectious disease (medical specialty) , medicine , disease , pathology
The base sequence homology between all eight 32P-labelled RNA segment of fowl plague virus (FPV) and the complementary RNA (cRNA) of an influenza B virus (B-mass), and between segment 8 of virus N and the cRNA of the same influenza B strain has been determined. All segments of FPV and segment 8 of virus N show a significant base sequence homology, ranging from 18 to 50% suggesting that influenza A and B viruses have a common ancestor. The conserved regions in segments 4,6 and 8 of the influenza A strains are identical to corresponding regions of the influenza B virus tested.