Open AccessIs Interferon Tissue Specific? -- Effect of Human Leukocyte and Fibroblast Interferons on the Growth of Lymphoblastoid and Osteosarcoma Cell Lines
Author(s) -
Stefan Einhorn,
Hans Strander
Publication year - 1977
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/0022-1317-35-3-573
Subject(s) - fibroblast , lymphoblast , biology , interferon , osteosarcoma , in vitro , cell , cell growth , cell culture , immunology , cancer research , virology , microbiology and biotechnology , biochemistry , genetics
The growth inhibitory effect of human leukocyte and fibroblast interferons was tested in vitro. The effect of fibroblast interferon was more pronounced on osteosarcoma cells and the effect of leukocyte interferon was more pronounced on lymphoid cells. This suggests that the capacity of interferon to inhibit cell growth is, in some measure, tissue specific.