Open AccessRequirement of the Bacteriophage T7 0.7 Gene for Phage Growth in the Presence of the Col 1b Factor
Author(s) -
Belén Gómez,
L Nualart
Publication year - 1977
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/0022-1317-35-1-99
Subject(s) - biology , virology , mutant , bacteriophage , lysis , virus , gene , microbiology and biotechnology , escherichia coli , genetics
A variety of colicinogenic factors were examined for their effect on the growth of phages related to T7. Col B1 and Col B4 inhibited the growth of every phage tested. Col B2, however, did not interfere with T3 and H. Col E2 interfered only with growth of T3, while Col Ib produced abortive infection with some T7 mutants. The abortive infection associated with Col Ib seems to be correlated with the absence of the virus phosphokinase; mixed infection with T7 wild type and a phosphokinase deficient mutant was productive but the phage yield was depressed. The abortively infected cells lysed.