Open AccessVesicular Stomatitis Virus: Mode of Transcription
Author(s) -
Amiya K. Banerjee,
Gordon Abraham,
Richard J. Colonno
Publication year - 1977
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/0022-1317-34-1-1
Subject(s) - biology , transcription (linguistics) , vesicular stomatitis virus , virology , rna polymerase , rna polymerase ii , rna , messenger rna , polymerase , vesicular stomatitis indiana virus , rhabdoviridae , gene , virus , genetics , promoter , gene expression , philosophy , linguistics
Recent studies on the mechanism by which the virion-associated RNA polymerase of vesicular stomatitis virus transcribes RNA have revealed several new biological features of general interest. The mode of synthesis of the 5'-terminal cap structure of the mRNAs, the sequential transcription of the genes and the presence of a transcribed "leader" RNA segment are properties which are either not shown by other viruses, or have not yet been described. These features are probably inter-related with the primary transcription process, which itself may be a useful model for future studies on mRNA biosynthesis in eukaryotic systems.