Open AccessFamilial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons
Author(s) -
Jocelyn Widagdo,
Saumya R. Udagedara,
Nishita Bhembre,
Jing Zhi Anson Tan,
Lara Neureiter,
Jie Huang,
Victor Anggono,
Lee M
Publication year - 2022
Publication title -
open biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.078
H-Index - 53
ISSN - 2046-2441
DOI - 10.1098/rsob.220187
Subject(s) - biology , rna binding protein , cytoplasm , microbiology and biotechnology , splicing factor , stress granule , protein subunit , mutant , wild type , zinc finger , alternative splicing , genetics , rna , transcription factor , gene , messenger rna , translation (biology)