Open AccessSwimming exercise reverses chronic unpredictable mild stress–induced depression-like behaviors and alleviates neuroinflammation and collapsing response mediator protein-2–mediated neuroplasticity injury in adult male mice
Author(s) -
Yumeng Xie,
Zuotian Wu,
Lihua Sun,
Lin Zhou,
Ling Xiao,
Huiling Wang,
Gaohua Wang
Publication year - 2022
Publication title -
neuroreport/neuroreport
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.607
H-Index - 188
eISSN - 1473-558X
pISSN - 0959-4965
DOI - 10.1097/wnr.0000000000001779
Subject(s) - neuroinflammation , open field , behavioural despair test , neuroplasticity , medicine , tail suspension test , elevated plus maze , endocrinology , hippocampus , overtraining , psychology , neuroscience , inflammation , anxiety , physical therapy , psychiatry , antidepressant , athletes
Impaired neuroplasticity and neuroinflammation are vital in the mechanisms of depression. Exercise alleviates depressive symptoms and ameliorates body functions. Swimming is one of the most common exercises; however, whether swimming alters depressive behaviors and the underlying mechanism has not been fully elucidated.