Open AccessCortical Excitability, Synaptic Plasticity, and Cognition in Benign Epilepsy With Centrotemporal Spikes: A Pilot TMS-EMG-EEG Study
Author(s) -
F Bäumer,
Kristina J. Pfeifer,
Adam Fogarty,
Dalia Pena-Solorzano,
Camarin E. Rolle,
Jenelle Wallace,
Alexander Rotenberg,
Robert S. Fisher
Publication year - 2020
Publication title -
journal of clinical neurophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.657
H-Index - 99
eISSN - 1537-1603
pISSN - 0736-0258
DOI - 10.1097/wnp.0000000000000662
Subject(s) - transcranial magnetic stimulation , motor cortex , n100 , neuroscience , psychology , epilepsy , audiology , electroencephalography , neuroplasticity , medicine , stimulation , event related potential
Children with benign epilepsy with centrotemporal spikes have rare seizures emerging from the motor cortex, which they outgrow in adolescence, and additionally may have language deficits of unclear etiology. We piloted the use of transcranial magnetic stimulation paired with EMG and EEG (TMS-EMG, TMS-EEG) to test the hypotheses that net cortical excitability decreases with age and that use-dependent plasticity predicts learning.