Open AccessPerineural Spread of Cancer Along the Three Trigeminal Divisions
Author(s) -
Kara F Warden,
Hemant Parmar,
Jonathan D. Trobe
Publication year - 2009
Publication title -
journal of neuro-ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 55
eISSN - 1536-5166
pISSN - 1070-8022
DOI - 10.1097/wno.0b013e3181b1b39a
Subject(s) - perineural invasion , head and neck , medicine , trigeminal nerve , head and neck cancer , anatomy , cancer , surgery
Perineural spread of head and neck cancers is a well-documented phenomenon, but the diagnosis is often delayed due to lack of familiarity with clinical manifestations, anatomy of the head and neck, and imaging signs. We present single cases of perineural spread along each of the 3 divisions of the trigeminal nerve in which the perineural spread was initially overlooked. Although perineural spread is often associated with a poor prognosis, earlier detection may improve outcome.