Open AccessCross-Sectional Analysis of Baseline Visual Parameters in Subjects Recruited Into the RESCUE and REVERSE ND4-LHON Gene Therapy Studies
Author(s) -
Mark L. Moster,
Robert C. Sergott,
Nancy J. Newman,
Patrick YuWaiMan,
Valerio Carelli,
Molly Scannell Bryan,
Gerard Smits,
Valérie Biousse,
C. Vignal-Clermont,
Thomas Klopstock,
Alfredo A. Sadun,
Adam A DeBusk,
Michele Carbonelli,
Rabih Hage,
Siegfried Priglinger,
Rustum Karanjia,
Laure Blouin,
Magali Taiel,
Barrett Katz,
J Sahel
Publication year - 2021
Publication title -
journal of neuro-ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 55
eISSN - 1536-5166
pISSN - 1070-8022
DOI - 10.1097/wno.0000000000001316
Subject(s) - medicine , ophthalmology , visual acuity , nerve fiber layer , optical coherence tomography , retinal , visual field , cross sectional study , clinical trial , pathology
This report presents a cross-sectional analysis of the baseline characteristics of subjects with Leber hereditary optic neuropathy enrolled in the gene therapy trials RESCUE and REVERSE, to illustrate the evolution of visual parameters over the first year after vision loss.