Open AccessMacular Ganglion Cell and Inner Plexiform Layer Thickness Is More Strongly Associated With Visual Function in Multiple Sclerosis Than Bruch Membrane Opening–Minimum Rim Width or Peripapillary Retinal Nerve Fiber Layer Thicknesses
Author(s) -
James Nguyen,
Alissa Rothman,
Natalia Gonzalez,
Ama Avornu,
Esther Ogbuokiri,
Laura J. Balcer,
Steven Galetta,
Elliot M. Frohman,
Teresa C. Frohman,
Ciprian M. Crainiceanu,
Peter A. Calabresi,
Shiv Saidha
Publication year - 2019
Publication title -
journal of neuro-ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 55
eISSN - 1536-5166
pISSN - 1070-8022
DOI - 10.1097/wno.0000000000000768
Subject(s) - nerve fiber layer , medicine , bruch's membrane , ophthalmology , retinal , expanded disability status scale , inner plexiform layer , visual acuity , optical coherence tomography , ganglion , multiple sclerosis , ganglion cell layer , anatomy , retinal pigment epithelium , psychiatry
Optical coherence tomography (OCT) measurements of ganglion cell + inner plexiform layer (GCIPL) and peripapillary retinal nerve fiber layer (pRNFL) thicknesses are associated with visual function (VF) and disability in multiple sclerosis (MS). However, the value of measuring Bruch membrane opening-minimum rim width (BMO-MRW) thickness in MS remains unclear.