Open AccessAquaporin-4 Serostatus and Visual Outcomes in Clinically Isolated Acute Optic Neuritis
Author(s) -
Edgar Carnero Contentti,
Mariana De Virgiliis,
Javier Hryb,
Ana-María Gómez,
Sergio Morales,
J. Celso,
Felisa Leguizamón,
Edson Chiganer,
José Luis Di Pace,
Carmen Lessa,
Mónica Perassolo
Publication year - 2019
Publication title -
journal of neuro-ophthalmology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.586
H-Index - 55
eISSN - 1536-5166
pISSN - 1070-8022
DOI - 10.1097/wno.0000000000000668
Subject(s) - optic neuritis , serostatus , ophthalmology , medicine , neuroscience , audiology , psychology , multiple sclerosis , immunology , human immunodeficiency virus (hiv) , viral load
Aquaporin-4 antibodies (AQP4-Ab) are associated with neuromyelitis optica spectrum disorder (NMOSD) and typically this disorder has a poor visual prognosis as a result of optic neuritis (ON). Our aim was to report the clinical features at onset and final visual outcomes at 6 months of patients with ON who were positive for AQP4-Ab vs. those who were negative for AQP4-Ab.