Open AccessThe role of innate immune genes in Alzheimer's disease
Author(s) -
Ana Griciuc,
Rudolph E. Tanzi
Publication year - 2021
Publication title -
current opinion in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 119
eISSN - 1473-6551
pISSN - 1350-7540
DOI - 10.1097/wco.0000000000000911
Subject(s) - neuroinflammation , trem2 , microglia , neurodegeneration , innate immune system , alzheimer's disease , immunology , immune system , medicine , biology , disease , inflammation , pathology
The aim of this study was to provide an update on the role of the innate immune system and neuroinflammation in the pathogenesis of Alzheimer's disease, with an emphasis on microglial receptors CD33 and TREM2.