Open AccessWhere are we moving in the classification of idiopathic inflammatory myopathies?
Author(s) -
Jantima Tanboon,
Akinori Uruha,
Werner Stenzel,
Ichizo Nishino
Publication year - 2020
Publication title -
current opinion in neurology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 119
eISSN - 1473-6551
pISSN - 1350-7540
DOI - 10.1097/wco.0000000000000855
Subject(s) - dermatomyositis , polymyositis , inclusion body myositis , myositis , medicine , inflammatory myopathy , juvenile dermatomyositis , immunology , muscle biopsy , population , pathology , biopsy , environmental health
Discoveries of myositis-specific antibodies, transcriptomic signatures, and clinicoseropathological correlation support classification of idiopathic inflammatory myopathies (IIM) into four major subgroups: dermatomyositis, immune-mediated necrotizing myopathy (IMNM), antisynthetase syndrome (ASS), and inclusion body myositis (IBM) whereas leaving polymyositis as a historical nonspecific diagnosis of exclusion. This review summarizes and comments on recent knowledge regarding the major subgroup of IIM.